LHY — Arabidopsis thaliana

Summary

AT1G01060 (LHY, LATE ELONGATED HYPOCOTYL) encodes a Myb/SANT domain-containing protein with DNA-binding transcription activator activity, RNA polymerase II-specific, and additional molecular functions including protein kinase regulator activity, histone H3K9 acetyltransferase activity, and chromatin DNA binding. LHY is associated with circadian behavior, temperature compensation of the circadian clock, and photomorphogenesis. The gene is linked to numerous agronomic traits including photoperiod sensitivity, flowering time, stem length, leaf area, seedling height, drought recovery, and heterosis. LHY localizes to the nucleus, nucleolus, cytosol, and mitochondria, and is associated with pathways regulating CCA1, PRR1/TOC1, and PRR95 expression, as well as ubiquitin-mediated degradation of TOC1. Studies of related genes in other species connect the LHY family to circadian rhythms, flowering time, and stress responses.