AXR1 — Arabidopsis thaliana

Summary

AT1G05180 (AXR1) of Arabidopsis thaliana encodes a protein with RUB1 activating enzyme activity, ubiquitin-like modifier activating enzyme activity, and NEDD8 transferase activity. It contains APP-BP1 and ThiF/MoeB/HesA domains. AXR1 is associated with biological processes including protein neddylation, response to gravity, differential growth, strigolactone anabolism, anthocyanin accumulation in response to UV light, and DNA damage tolerance. The gene is linked to traits such as biomass production, inflorescence size, root number, lateral root length, root hair density, shoot branching, stamen and anther morphology, phototropism, herbicide resistance and sensitivity, fungal resistance, ammonium tolerance, and auxin, brassinosteroid, ethylene and cytokinin sensitivity. AXR1 localizes to the nucleus, cytosol, endoplasmic reticulum, plasmodesma, mitochondria and plasma membrane.