CS1 — Arabidopsis thaliana

Summary

AT1G07890 (CS1/APX1) in Arabidopsis thaliana encodes a cytosolic L-ascorbate peroxidase 1 (EC 1.11.1.11), a haem peroxidase that also exhibits p-coumarate 3-hydroxylase, siRNA/miRNA binding, chitosan binding, RNA endonuclease, histone H2AS1 kinase, transmembrane receptor protein kinase, and protein kinase activities. The gene is associated with tolerance to salt, heat, oxidative, high-light, ozone, sulfur dioxide, and iron stresses, as well as root development, hydrotropism, hydrogen peroxide accumulation, and iron-regulated gene expression. It has been linked to traits including bacterial blight and viral disease resistance, aphid response, photosynthetic ability, seed viability, carpel and floral organ number, phyllotaxy, leaf curling, starch and cytokinin content, days to flowering, and meristem identity. The protein localizes to the cytosol, stress granules, cell wall, chloroplast stroma, Golgi, plasmodesmata, and plasmalemma, and is associated with the ascorbate-glutathione cycle, cell cycle checkpoints, mitophagy, stomatal development, and responses to UV-A and paraquat.