DFR — Arabidopsis thaliana

Summary

AT5G42800, also known as DFR (DIHYDROFLAVONOL 4-REDUCTASE) or TT3, encodes a flavanone 4-reductase with dihydroflavanol 4-reductase, flavonol synthase, and chalcone isomerase activities. This Arabidopsis thaliana gene on chromosome 5 is associated with flavonoid, anthocyanin, and proanthocyanidin biosynthesis, as well as pigmentation, photoprotection, and response to gravity. It has been linked to numerous traits including anthocyanin and flavonoid content, seed coat pigmentation, UV light sensitivity, photosynthetic ability, transpiration rate, root morphology, and responses to abiotic stresses such as drought, salt, low temperature, and oxidative stress. The gene is also connected to herbicide sensitivity, insect damage response, stamen morphology, flower development, and pollen fertility restoration. Localization evidence places the product in the cytosol, nucleus, endoplasmic reticulum, and tonoplast.