HSP70 — Arabidopsis thaliana

Summary

AT4G16660, designated HSP70 or HSP70-17 in Arabidopsis thaliana, encodes a heat shock 70 kDa protein family member that is an ATP-dependent protein folding chaperone with ATP binding activity. The gene is associated with diverse biological processes including protein denaturation and unfolding, pyruvate metabolism, nuclear division, karyogamy, protein farnesylation, cellular respiration, glycan biosynthesis, digestion, protein modification, jasmonic acid anabolism, ER stress response, double fertilization, hypersensitivity, induced systemic resistance, syngamy, and anther development. It localises to the ER lumen, secretory vesicles, ER, plant-type vacuole, Golgi complex, and cytosol. The gene is associated with traits such as radiation response, germination rate, abiotic plant stress response, photosynthetic rate, and salt tolerance, as well as phenotypes including heat stress response, thermal stress tolerance, thermotolerance, wound response, and heat shock response. Studies of related genes in other species link the family to heat, drought, and salt stress tolerance.