PYR1 — Arabidopsis thaliana

Summary

AT4G17870 (PYR1) in Arabidopsis thaliana encodes a protein with abscisic acid binding, protein phosphatase inhibitor, protein phosphatase regulator, protein kinase activator, kinase regulator, signaling receptor, and lipid binding activities, belonging to the polyketide cyclase/dehydrase and START-like domain superfamilies. PYR1 is associated with abscisic acid signaling, release of seed from dormancy, regulation of stomatal opening, and response to water. It has been linked to traits including drought recovery, leaf water potential, seed yield, biomass yield, starch mobilization, and vegetative vigor. The gene is associated with flavone metabolism, chlorophyll breakdown, starch breakdown, and cytokinesis. PYR1 localizes to the cytosol, nucleus, tonoplast, and plasmalemma, and is associated with ABA-mediated signaling pathways and PP2C:SAPK8 complex formation. Studies of related genes in other species link the family to fruit development, adventitious root formation, and stress tolerance traits.