CHS4 — Arabidopsis thaliana

Summary

AT4G20380 (CHS4/LSD1) in Arabidopsis thaliana encodes a zinc finger LSD1-type protein with S-nitrosylase activity, DNA-binding transcription factor activity, and co-ion binding. This gene is associated with cell death regulation, including negative regulation of the hypersensitive response and induction of programmed cell death, as well as drought tolerance, aerenchyma formation, and UV-C-induced programmed cell death. It is linked to regulation of superoxide removal and hydrogen peroxide metabolism, and to responses to UV-A, UV-C, and superoxide. The product localizes to multiple cellular compartments including the chloroplast envelope, stromule, apoplast, and plasmodesma. Associations with agronomic traits include seed yield, biomass yield, root morphology, leaf size, stomatal closure, disease tolerance, and responses to abiotic stresses such as low temperature and salt. Studies of related genes in other species link the family to chlorophyll content and root morphology traits.