GA5 — Arabidopsis thaliana

Summary

AT4G25420 (GA5) encodes gibberellin 20-oxidase 1, a 2-oxoglutarate-dependent dioxygenase that catalyses multiple steps in gibberellin biosynthesis, converting gibberellins such as GA12, GA44, GA19, GA53, GA15, GA14, GA24 and GA36. The enzyme belongs to the iron/ascorbate oxidoreductase and IPNS-like dioxygenase families and localises to the cytoplasm. In Arabidopsis, GA5 is associated with stem growth, internode and shoot elongation, anther filament elongation, silique length and density, seed development, and gibberellin feedback regulation. The gene has been linked to numerous traits including plant height, flowering time, seed germination and dormancy, root length and thickness, leaf area and morphology, chlorophyll content, drought tolerance, disease resistance, and fruit growth and development. It is also associated with responses to light, oxygen, hormones, and thermomorphogenesis. Studies of related genes in other species link the family to fruit development, parthenocarpy, salt tolerance, and leaf complexity.