SUM1 (AT4G26840) — Arabidopsis thaliana

Summary

AT4G26840, designated SUM1 (SUMO 1) in Arabidopsis thaliana, encodes a small ubiquitin-like modifier (SUMO) protein containing a Rad60/SUMO-like domain and a ubiquitin-like domain. The gene has been annotated with numerous molecular functions including malate synthase, aminomethyltransferase, and phosphoglucomutase activities, among many others. SUM1 is associated with DNA replication, thermo-resilience, basal immunity, and ABA-mediated growth inhibition in Arabidopsis. It has been linked to biological processes such as negative regulation of ubiquitin-dependent protein catabolism, cellular response to metal, pantothenate anabolism, plant epidermis morphogenesis, and flower structural organization. The protein localizes to various cellular compartments including the nuclear matrix, cohesin complex, photosystem I reaction center, and ER body. Associations with agronomically relevant traits include drought stress response, germination ratio, root width, starch grain size, chlorophyll ratio, and resistance to Meloidogyne incognita.