HA2 — Arabidopsis thaliana

Summary

AT4G30190 (HA2, also known as AHA2) on chromosome 4 of Arabidopsis thaliana encodes a P-type ATPase (EC 7.1.2.1) with proton-transporting ATPase activity. This gene is associated with proton export across the plasma membrane, vacuolar acidification, nitrate import, halotropism, and response to pH. HA2 is linked to salinity tolerance, iron deficiency tolerance, root hydrotropism, and embryo development. Additional associations include mineral and ion transport, water stress response, bacterial disease response, transpiration rate, and brassinosteroid sensitivity. The encoded protein localizes to the plasma membrane and has also been connected to the tonoplast, ER membrane, and nuclear envelope. Studies of related genes in other species link the HA2 family to traits including tuber yield, oxidative stress tolerance, and stomatal conductance.