ELG (AT4G33430) — Arabidopsis thaliana

Summary

AT4G33430 (ELG, also known as BAK1, SERK3) encodes a transmembrane receptor protein serine/threonine kinase, classified as EC 2.7.10.1. The product exhibits diverse molecular functions including calcium-dependent phospholipid binding, NAD(P)H oxidase H2O2-forming activity, guanylyl cyclase activity, GTPase inhibitor activity, channel regulator activity, peptide binding, and transcription regulator activity. In Arabidopsis, BAK1 is associated with viral resistance, nematode resistance, systemic disease resistance, immune perception of yeast cell walls, autoimmunity, plant growth and development, seed production, and lodging resistance. The gene is linked to numerous biological processes including immune response-regulating signaling pathways, regulation of autophagy, chemical homeostasis, paracrine signaling, and responses to humidity. Localization evidence connects the product to the heterotrimeric G-protein complex, endosome membrane, nuclear envelope, and ribosome. Studies of related genes in other species link the BAK1 family to Verticillium resistance, potato aphid resistance, virus resistance, and adventitious root development.