RAC3 — Arabidopsis thaliana

Summary

AT4G35020, also known as RAC3, ROP6, or AtRop6, encodes a member of the small GTPase Rho family in Arabidopsis thaliana. The product is annotated with multiple molecular functions including GDP binding, GTPase activity, and protein prenyltransferase activities. RAC3 is associated with the regulation of morphogenesis, cell polarization, actin and microtubule dynamics, endocytosis, and calcium-mediated signaling. Observed phenotypes link the gene to leaf and plant morphology, plant size, reactive oxygen species distribution, endocytic uptake, and iron-deficiency response. The gene has been connected to a wide range of traits including yield, seed yield, root and lateral root architecture, petal and leaf morphology, auxin and abscisic acid content, phosphorus and cadmium responses, and hybrid incompatibility. Studies of related genes in other species link the family to pollen tube growth polarity, vesicular trafficking, and resistance to bacterial wilt and Phytophthora.