GRF2 — Arabidopsis thaliana

Summary

AT4G37740, also known as GRF2 or growth-regulating factor 2, encodes a transcription coactivator with DNA-binding and transcription factor activity, belonging to the GRF protein family characterized by QLQ and WRC domains. The protein localizes to the nucleus and is associated with the positive regulation of cell cycle, cell division, cell differentiation, and root meristem growth, as well as leaf senescence, flower development, and plant organ development. GRF2 has been linked to responses to gibberellin, nematodes, and salt stress, and to traits including leaf width and shape, seed weight, stem elongation, water use efficiency, anthocyanin content, flowering time, and root length. The gene is also associated with glucosinolate metabolism, adaxial/abaxial pattern specification, and regulation of gene expression. Related genes in other species link the family to fruit position, fruit length, days to flowering, plant stress response, and root morphology.