CKR1 — Arabidopsis thaliana

Summary

AT5G03280 (CKR1/EIN2) in Arabidopsis thaliana encodes a protein with dual-specificity protein kinase activity, histidine kinase activity, ethylene receptor activity, and metal ion transmembrane transporter activity, belonging to the NRAMP family. It is localized to the ER membrane and nucleus. CKR1 is associated with ethylene signaling and biosynthesis pathways, and has been linked to diverse phenotypes including aluminum tolerance, osmotic stress tolerance, susceptibility to necrotrophic pathogens, Fusarium head blight resistance, aphid resistance, root-knot nematode resistance, and ozone-induced leaf injury. It is also associated with traits such as yield, fruit ripening, seed size, leaf senescence, root elongation, submergence tolerance, and responses to iron deficiency, nitrate, and temperature stress. Studies of related genes in other species link the family to fruit ripening, lycopene biosynthesis, and disease resistance.