DREB2 — Arabidopsis thaliana

Summary

AT5G05410 (DREB2A) in Arabidopsis thaliana encodes a protein with an AP2/ERF DNA-binding domain, annotated with DNA binding, transcription cis-regulatory region binding, transcription coactivator activity, NAD ADP-ribosyltransferase activity, and ubiquitin-protein transferase activity. DREB2A is associated with responses to dehydration, drought, heat, cold, and freezing stress, and with enhanced dehydration and osmotic stress tolerance. It is linked to biomass, water use efficiency, transpiration rate, leaf water potential, yield, and germination rate. The gene is associated with positive regulation of leaf senescence, upregulation of chlorophyll breakdown, starch breakdown, pyruvate metabolism, cellular respiration, jasmonic acid anabolism, nitric oxide anabolism, and glucose-mediated signalling. DREB2A localises to the nucleus, cytoplasm, nucleolus, and RNA polymerase II, IV, and V complexes, as well as the Mediator complex. Studies of related genes in other species link the family to grain size and tuber induction.