DMT7 — Arabidopsis thaliana

Summary

AT5G14620 (DMT7, also known as DRM2) encodes a domains rearranged methyltransferase 2, a DNA (cytosine-5-)-methyltransferase with siRNA binding and chromatin binding activities. This Arabidopsis thaliana gene is associated with retrotransposon silencing by RdDM, DNA methylation-dependent heterochromatin assembly, and RNAi-like chromatin silencing. It is linked to megasporocyte differentiation, tissue regeneration, DNA imprinting, and male meiotic nuclear division. The protein localizes to chromatin, the RNA Polymerase V complex, and the PRC2 complex. DMT7 is associated with traits including plastochron, shoot growth angle, phototropism, lateral root length, and adventitious rootless. It is also linked to seed viability, pollen fertility, flavonoid and phenolic compound content, UV light sensitivity, and salt response. Studies of related genes in other species connect the family to nematode resistance, disease resistance, and transposable element silencing.