KAN — Arabidopsis thaliana

Summary

AT5G16560 (KAN, KANADI 1) on Arabidopsis thaliana chromosome 5 encodes a transcription factor with DNA-binding and protein homodimerization activity, belonging to the KANADI family of Myb-domain proteins. It is associated with abaxial cell fate specification, adaxial/abaxial axis specification, radial pattern formation, and gynoecium development. The gene has been connected to leaf and floral organ identity, meristem determinacy, secondary growth, integument development, and cytokinin biosynthesis. Associations extend to traits including leaf size and morphology, seed size, fruit size, floral organ number, inflorescence size, phyllotaxy, yield, flowering time, auxin and brassinosteroid sensitivity, jasmonic acid content, seed dormancy, pollen fertility, and salt tolerance. The protein localizes to the nucleus and cytoplasm and is linked to strigolactone and brassinosteroid signaling pathways, chromatin looping, and regulation of salinity response. Studies of related genes in other species have connected the family to fruit firmness.