EDS5 — Arabidopsis thaliana

Summary

AT4G39030 (EDS5) in Arabidopsis thaliana encodes a MATE family transporter with antiporter activity and xenobiotic transmembrane transporter activity, localised to the chloroplast membrane and envelope. The gene is associated with salicylic acid biosynthesis, accumulation, signaling and defense responses, as well as pathogen resistance including nonhost resistance to Colletotrichum and Xanthomonas citri, resistance to Cucumber mosaic virus and Turnip crinkle virus, and broad-spectrum powdery mildew resistance. EDS5 is also linked to glucosinolate transport, camalexin anabolism, auxin transport, polyamine metabolism, and the MEP pathway. Phenotypic associations include disease resistance, cold tolerance, leaf chlorosis, and low temperature stress response. Studies of related MATE family members in other species link the family to induced systemic resistance and photochemical quenching.