GGP — Arabidopsis thaliana

Summary

AT4G26850, also known as GGP or VTC2, encodes a GDP-L-galactose phosphorylase (EC 2.7.7.69) belonging to the GDPGP family. The gene is associated with ascorbate metabolism, the ascorbate-glutathione cycle, nucleotide salvage, and responses to oxidative stress, light, and metals. It is linked to traits such as plant height, flowering time, photosynthetic rate, stomatal resistance, anthocyanin content, seed viability, and root length. Phenotypically, VTC2 is associated with ascorbate content, disease susceptibility to Alternaria brassicicola, ozone sensitivity, drought tolerance, salt tolerance, and aphid resistance. The protein localizes to both the cytoplasm and nucleus. Studies of related genes in other species link the family to fruit ripening, chilling tolerance, and vitamin C content.