RPP5 — Arabidopsis thaliana

Summary

AT4G16950, also known as RPP5, encodes a disease resistance protein in Arabidopsis thaliana. The product contains TIR, NB-ARC, and leucine-rich repeat domains and has been annotated with ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase activity, as well as nucleotide, ADP, ATP, and protein binding. RPP5 is associated with downy mildew resistance, specifically resistance to Peronospora parasitica, and with systemic acquired resistance, immune response, and innate immunity. The gene is also linked to programmed cell death, cell death, cell division, cell growth, pollen germination and tube growth, morphogenesis, protein phosphorylation, the stringent response, sporulation, nonsense-mediated mRNA decay, protein breakdown, and homeostasis. Additional associations include heterosis, arsenic concentration, disease tolerance, and dwarf plant phenotypes.