ORG3 — Arabidopsis thaliana

Summary

AT3G56980 (ORG3, bHLH39) encodes a basic helix-loop-helix (bHLH) transcription factor with DNA binding and protein dimerization activity, localised to the nucleus. ORG3 is associated with the regulation of iron transport, cellular response to iron ion starvation, multicellular organismal iron ion homeostasis, and response to iron. It is linked to traits including iron sensitivity, iron concentration, leaf chlorosis, root length, salt response, disease tolerance, and sucrose content. The gene is also associated with cadmium tolerance, iron accumulation, iron uptake, iron efficiency, drought tolerance, salt tolerance, and nutrient response. Studies of related bHLH family members in other species link the family to cadmium concentration, zinc sensitivity, chlorophyll content, oxidative stress response, flowering time, and root morphology traits.