MPK4 — Arabidopsis thaliana

Summary

AT4G01370 (MPK4) on Arabidopsis thaliana chromosome 4 encodes a mitogen-activated protein kinase (MAPK) with serine/threonine kinase activity, classified as EC 2.7.11.24, and exhibits MAPKKK binding, MAPK binding, and cis-regulatory region sequence-specific DNA binding. MPK4 is associated with stomatal immunity, reactive oxygen species burst, salicylic acid-mediated defense, jasmonic acid-induced defense, and fertility. It is linked to regulation of mitosis, cytokinesis, microtubule dynamics, thermomorphogenesis, and RNA surveillance. The protein localizes to the cell plate, microtubules, endosomes, plastids, mitochondria, cytosol, and plasmalemma. MPK4 has been connected to traits including tiller angle, seed volume, drought sensitivity, leaf width, brassinosteroid content, stem length, carotenoid content, and aluminum response. Related genes in other species are associated with enhanced susceptibility to Pseudomonas syringae and ascorbic acid content.