AFB1 — Arabidopsis thaliana

Summary

AT4G03190 (AFB1, also known as GRH1) encodes a protein with F-box and leucine-rich repeat domains. It is annotated with auxin receptor activity, NEDD8 transferase activity, ubiquitin-like protein transferase activity, auxin influx and efflux transmembrane transporter activities, and other molecular functions. The protein localizes to SCF complexes and the nucleus. AFB1 is associated with biological processes including SCF complex assembly, planar polarity establishment, cellular responses to nitrate and cyclopentenone, indole glucosinolate breakdown, and secondary metabolite biosynthesis. The gene is linked to traits such as root architecture (root shape, branching, hair density, adventitious root number), seedling cotyledon size, leaf morphology (margin serration, vein patterning), floral organ number and petal size, biomass yield, shoot fresh weight, phototropism, shade avoidance, heat and osmotic stress responses, aluminum and acid sensitivity, sodium and molybdenum content, and self-incompatibility. Related genes in other species connect the family to seedling vigor, fruit ripening, nitrate transport, salt response, and pathogen resistance.