FOU2 — Arabidopsis thaliana

Summary

AT4G03560, also known as FOU2 or TPC1, encodes a voltage-sensitive calcium channel that contains EF-hand domains and ion transport domains. This protein localizes to the vacuolar membrane and is associated with vacuolar cation channel activity, calcium ion influx, and calcium transport. TPC1 is associated with action potential, membrane depolarization, stomatal closure and movement, regulation of jasmonic acid biosynthetic process, autophagy, endocytosis, and exocytosis. The gene is linked to traits including calcium sensitivity, calcium concentration, jasmonic acid content, stomatal opening, stomatal complex closure time, salt stress tolerance, aphid resistance, fungal resistance, and radiation response. TPC1 is also associated with systemic calcium signaling, calcium wave propagation, calcium homeostasis, cation homeostasis, vacuolar excitability, vacuolar trafficking, germination, and defense gene expression. Related genes in other species are linked to salt tolerance.