EDS1 — Arabidopsis thaliana

Summary

AT3G48090, designated EDS1 (Enhanced Disease Susceptibility 1) in Arabidopsis thaliana chromosome 3, encodes a protein belonging to the EDS1-like family with an alpha/beta hydrolase fold and annotated SUMO-specific endopeptidase, carboxylesterase, lipase and ADP-ribosyl cyclase activities. EDS1 is associated with pattern-triggered immunity, disease resistance signaling, nonhost resistance, UV-C-induced programmed cell death and Fusarium graminearum resistance. It is linked to positive regulation of salicylic acid-mediated signaling, camalexin activation, reactive oxygen species metabolism, detection of insects, egg deposition, and downregulation of photosynthesis. The protein localises to the EDS1 disease-resistance complex, perinuclear cytoplasm, endomembrane system and nucleolus. Associations extend to yield, biomass, seed yield, heterosis, chlorophyll content, photosynthetic rate, stomatal resistance, flowering time, leaf senescence, and responses to bacterial, viral, aphid, powdery mildew and aluminum stress.