CDC2 — Arabidopsis thaliana

Summary

AT3G48750, also known as CDC2, CDC2A, or CDKA;1, encodes a cyclin-dependent kinase (CDK) in Arabidopsis thaliana. The gene product is a cyclin-dependent kinase that binds cyclins and exhibits cyclin-dependent protein serine/threonine kinase regulator activity. CDC2 is associated with cell cycle control, specifically G1/S phase progression, and with mitotic and meiotic exit. It is linked to numerous developmental and agronomic traits, including leaf attitude and elongation rate, root width and weight, inflorescence and petal size, stamen number, harvest index, total soluble sugar content, nitrate content, and submergence tolerance. The protein localizes to the cortical microtubule cytoskeleton, preprophase band, and male germ cell nucleus, and is connected to pathways such as starch and sucrose biosynthesis, glutathione redox reactions, and the formation and inactivation of CDKA:CycD complexes.