H2A.Z — Arabidopsis thaliana

Summary

AT3G54560 (HTA11, H2A.Z) encodes a histone H2A variant protein that is a structural constituent of chromatin and exhibits DNA binding, chromatin binding, protein heterodimerization activity, and multiple enzymatic activities including histone acetylase, deacetylase, and protein kinase activities. In Arabidopsis, H2A.Z is associated with thermomorphogenesis, temperature detection, regulation of chromatin organization, heterochromatin organization, DNA imprinting, memory, cytokinesis, shoot regeneration, petal formation and development, organogenesis, mitosis, vegetative phase change, lateral root development, gravitropic response, and reactive oxygen species production. The gene has been connected to numerous traits including flowering time, seed size, leaf size and morphology, photosynthetic rate, stomatal closure, high temperature stress response, germination rate, pedicel length, manganese sensitivity, trichome density, petal and gynoecium development, inflorescence and stamen morphology, stem senescence, biotic stress, jasmonic acid and cytokinin sensitivity and content, insect damage response, brassinosteroid sensitivity, and light intensity response.