CLM — Arabidopsis thaliana
Summary
AT3G50660 (DWF4, also known as CYP90B1) in Arabidopsis thaliana encodes a cytochrome P450 enzyme with steroid 22S-hydroxylase activity, and is annotated as a 6-oxocampestanol hydroxylase (EC 1.14.14.178). The gene is associated with brassinosteroid anabolism and homeostasis, shade avoidance, tropism, differential growth, leaf shaping, secondary growth, and transdifferentiation. It localizes to the endoplasmic reticulum and membrane. DWF4 is linked to vegetative growth, root biomass, seed yield, flowering time, hypocotyl growth, heat tolerance, drought tolerance, and disease resistance. Associations also include inflorescence height, brassinosteroid content, cell elongation, leaf size, root length and thickness, and thermotolerance. Studies of related genes in other species link the family to salt tolerance and fruit traits.
Annotations
- Chromosome
- 3
- Related genes
- CLM
- GO terms
- homeostasis, Hypersensitivity, Transdifferentiation, NO storage, Circadian Rhythm, iron binding, Leaf Development, GA-signaling
- Publications
- 28479230, 16960392, 22315138, 41024265, 12114578, Plant J 45(5);765-74, Plant J 26(6);573-82, PMID:18394996
- Traits
- brassinosteroid biosynthesis, plant height, cell elongation, dwarfism, Short Hypocotyls in Dark Conditions, Increased Hypocotyl Sensitivity to IAA Growth Inhibition, Normal Initial Gravitropic Curvature, Intermediate Curvature Over Time, Dwarf with Dark Green Round Leaves and Increased Lateral Shoots