PIP2 — Arabidopsis thaliana

Summary

AT3G53420 (PIP2;1, also known as PIP2A) on chromosome 3 of Arabidopsis thaliana encodes a plasma membrane intrinsic protein belonging to the aquaporin family, with water channel activity and phospholipase D activity. The gene is associated with water transport, hydraulic conductivity, and stomatal movement, as well as hydrogen peroxide transport and oxidative stress response. It has been linked to seed germination under salinity, waterlogging stress response, and circadian regulation of water dynamics. Additional associations include sodium uptake, phosphorus response, leaf water potential, seed weight, net photosynthetic rate, starch content, salt response, drought tolerance, freezing tolerance, and disease resistance. The protein localizes to the plasma membrane, plasmodesmata, and other cellular compartments, and is connected to phosphatidic acid metabolism, endocytic recycling, and regulation of programmed cell death. Studies of related genes in other species link the family to pathogen response and resistance to Pseudomonas syringae.