FHY3 — Arabidopsis thaliana

Summary

AT3G22170, also known as FHY3 (far-red elongated hypocotyls 3) and CPD45, encodes a FAR1-RELATED SEQUENCE protein with DNA-binding transcription activator activity, RNA polymerase II-specific, and is associated with phytochrome binding, far-red light photoreceptor activity, and protein kinase activity. The gene is associated with regulation of chloroplast fission, far-red light signaling, circadian clock rhythmicity, and response to very low fluence red light and continuous far-red light. FHY3 has been linked to numerous agronomic traits including grain yield, panicle number, leaf area index, seedling height, drought recovery, photoperiod sensitivity, leaf chlorophyll content, and heterosis. It localizes to the nucleus, nuclear body, cytoplasm, and plasma membrane, and is connected to pathways involving CCA1 expression and phosphorylation, PHYA activation and translocation, and HY5 degradation. Studies of related genes in other species link the family to plant height and grain yield.