RGS1 — Arabidopsis thaliana

Summary

AT3G26090, known as RGS1 (REGULATOR OF G-PROTEIN SIGNALING 1) in Arabidopsis thaliana, encodes a protein with GTPase inhibitor activity, GTP binding, and GAP activity, featuring RGS (regulator of G-protein signaling) domains. This gene is associated with G-protein and sugar signaling, glucose sensing and response, cell proliferation and elongation, and flg22-induced ROS production. It has been linked to photosynthesis efficiency, clathrin-mediated endocytosis, protein trafficking, and abscisic acid sensitivity. RGS1 is associated with numerous traits including grain size, seed yield, germination rate, root and hypocotyl length, stomatal movement and closure, drought and temperature stress tolerance, disease resistance, and nitrate sensitivity. The protein localizes to the plasma membrane, endosome, endoplasmic reticulum, and heterotrimeric G-protein complex, and is associated with GPCR signaling, MAPK cascade, autophagy, and reactive oxygen species-mediated programmed cell death.