LOX2 — Arabidopsis thaliana

Summary

AT3G45140 (LOX2) on chromosome 3 of Arabidopsis thaliana encodes a lipoxygenase with linoleate 13S-lipoxygenase and linolenate 13S-lipoxygenase activities (EC 1.13.11.12). The protein contains lipoxygenase and PLAT/LH2 domains and is associated with jasmonate biosynthesis and jasmonate-induced defense responses, as well as resistance to fungal pathogens, herbivory, and necrotrophic pathogens. LOX2 has been connected to green leaf volatile and five-carbon volatile biosynthesis, wound response gene expression, and abiotic stress tolerance. The gene is linked to traits including leaf necrosis, seed weight, seed yield, chlorophyll content, photosynthetic rate, carotenoid content, and photoperiod-sensitive flowering time. The protein localizes to chloroplast thylakoid membranes, stromules, and stress granules, and participates in the 13-LOX and 13-HPL pathway. Related genes in other species link the family to oxylipin biosynthesis, wound response, and anther maturation.