ERD5 — Arabidopsis thaliana

Summary

AT3G30775, also known as ERD5, PRO1, or PDH1, encodes a proline dehydrogenase (EC 1.5.5.2) with proline oxidase activity, a FAD-linked oxidoreductase localized to mitochondria. This gene is associated with proline breakdown and catabolism, arginine breakdown, pyruvate metabolism, cellular respiration, and the electron transport chain. It is linked to response to dehydration, osmotic stress, oxidative stress, low temperature, and glyphosate sensitivity. Traits associated with ERD5 include drought recovery, proline content, amino acid content, photosynthetic rate, respiration rate, and disease tolerance. Phenotypes linked to this gene include proline accumulation and degradation, reactive oxygen species accumulation, decreased root elongation under low water potential, and altered NADP/NADPH ratios. Studies of related genes in other species link the family to heat stress tolerance and salt tolerance.

Annotations

Chromosome
3
Related genes
ERD5, PDH2
GO terms
homeostasis, Hypersensitivity, protein synthesis, response to Gly, Response To Proline, Memory, Protein Dehydration, Translation
Publications
17172353, 23858430, 20736450, 20883441, 28831155, 27526663, 27303048, 37843921
Traits
glyphosate sensitivity, abiotic stress response, osmotic stress tolerance, proline homeostasis, proline metabolism, osmotic stress response, dehydration response, reproductive development