PHO1 — Arabidopsis thaliana
Summary
AT3G23430, also known as PHO1 or ARABIDOPSIS PHOSPHATE 1, encodes a protein containing SPX and EXS domains with phosphate transmembrane transporter activity, inositol hexakisphosphate (IP6) binding, and ubiquitin-protein transferase activity. In Arabidopsis, PHO1 is associated with phosphate loading to xylem, arsenic accumulation, and regulation of phosphate membrane transport. The gene is linked to intracellular phosphate homeostasis, polyphosphate signaling, and the anabolism of sulfolipids, galactolipids, starch, and sucrose. PHO1 has been connected to shoot phosphorus and phosphate content, root hair density, shoot growth angle, carbohydrate content, leaf senescence, flowering time, and responses to low temperature and abscisic acid. The protein localizes to the endomembrane system, including the Golgi, endoplasmic reticulum, and plasma membrane. Studies of related genes in other species link the family to root morphology and phosphorus response.
Annotations
- Chromosome
- 3
- Related genes
- PHO1, T9I1.12, PHO2, PHO1-H3, T18E12.7, T18E12.8, T18E12.9, AT1G26730
- GO terms
- homeostasis, ARR, syngamy, polyphosphate signaling, NO storage, Acid Secretion, Endosome, cytokinin signaling
- Publications
- 12969422, 17172353, 16132859, 17085508, 23858430, 26556605, 20521954, 18631293
- Traits
- fungal pathogen resistance, phosphorus utilization, phosphate acquisition, phosphate uptake, phosphate accumulation, phosphate translocation, No Observable Growth or Phosphate Transport Defects, Reduced Growth and Impaired Root-to-Shoot Phosphate Transfer