AGC2 — Arabidopsis thaliana

Summary

AT3G25250, also known as AGC2 or OXI1, encodes a protein serine/threonine kinase with 3-phosphoinositide-dependent protein kinase activity, protein tyrosine kinase activity, and phosphatidate binding. In Arabidopsis, this gene is associated with photooxidative stress sensitivity, growth promotion by Piriformospora indica, and responses to salinity and abiotic stimuli. It is linked to root structure development, vegetative structure development, and MAP kinase signaling pathways (MPK3, MPK5, MPK6). The gene is associated with traits including root hair length, adventitious root number, salt response, aphid response, UV-B light sensitivity, and jasmonic acid sensitivity. It localizes to the cytosol, plasmalemma, and plasmodesma, and is associated with processes such as stomatal complex patterning, pollen-pistil interaction, and cellular response to stress. Studies of related genes in other species link the family to photosynthetic rate, water use efficiency, and disease susceptibility.