PIN3 — Arabidopsis thaliana

Summary

AT1G70940, designated PIN3 in Arabidopsis thaliana, encodes an auxin efflux carrier protein belonging to the PIN-FORMED family, with additional annotated molecular functions including inositol-1,4-bisphosphate 1-phosphatase activity, phosphatidylinositol phosphate binding, and clathrin binding. PIN3 is associated with tropism, differential growth, and root meristem growth, and has been connected to gravity response, phototropism, and blue light sensitivity traits. The gene is linked to auxin signalling, regulation of seed size, seed development, and reproductive structure development pathways. PIN3 localises to the basal plasma membrane, recycling endosome, and clathrin-coated endocytic vesicle. Studies of related genes in other species link the PIN3 family to shoot architecture, leaf flattening, parthenocarpic fruit development, and insect resistance.