MYCGR3G67035 — Zymoseptoria tritici

Summary

The Zymoseptoria tritici gene ppoA (MYCGR3G67035) on chromosome 1 encodes a protein with linoleate 8R-lipoxygenase, 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase, fatty acid peroxidase, dioxygenase, peroxidase, isomerase, oxidoreductase, monooxygenase, iron-binding, and heme-binding activities. It belongs to the Ppo_N, haem peroxidase, and cytochrome P450 superfamilies. This gene is associated with oxylipin and prostaglandin anabolism, fatty acid metabolism, penicillin and sterigmatocystin metabolism, hydrogen peroxide catabolism, and response to oxidative stress. It is linked to both positive regulation of asexual sporulation and negative regulation of sexual sporulation, as well as general sporulation processes. Studies of related genes in other species connect this family to altered virulence, including hypervirulence and reduced virulence, though these effects are not established for ppoA itself.