MYCGR3G71165 — Zymoseptoria tritici

Summary

MYCGR3G71165 (symbol ppoA) on Zymoseptoria tritici chromosome 4 encodes a linoleate 8R-lipoxygenase with fatty acid peroxidase, dioxygenase, isomerase, monooxygenase, and heme-iron binding activities. It belongs to the oxylipin biosynthesis and haem peroxidase superfamilies. The gene is associated with oxylipin and prostaglandin anabolism, fatty acid metabolism, and hydrogen peroxide catabolism. It is linked to both positive regulation of asexual sporulation and negative regulation of sexual sporulation, as well as general sporulation and response to oxidative stress. Associations with penicillin and sterigmatocystin metabolism are also noted. Studies of related genes in other species link the family to altered virulence, including hypervirulence and reduced virulence, though these phenotypes are not established for this specific gene.