MYCGR3G70094 — Zymoseptoria tritici

Summary

MYCGR3G70094 (FUS3) on Zymoseptoria tritici chromosome 3 encodes a dual-specificity protein kinase with serine/threonine and tyrosine kinase activities, ATP and calmodulin binding, and chromatin binding. It is associated with regulation of filamentous growth, seed maturation and development, pigment accumulation, polyol anabolism, intracellular glycerol accumulation, osmolarity sensing, cellular responses to nitrosative stress and cadmium, regulation of mRNA processing, nuclear cell cycle DNA replication, reciprocal meiotic recombination, and mitochondrion organization. The gene is linked to downregulation of filamentous growth in response to biotic stimuli and heat, and downregulation of protein localisation in the plasma membrane and exit from mitosis. Localisation includes the cell tip, lateral cell cortex, cytoskeleton, chromatin, and mitotic actomyosin contractile ring. Related genes in other species link the family to mitogen-activated protein kinase activity (EC 2.7.11.24), and associations with virulence and oxidative stress tolerance.