TH7 — Triticum turgidum subsp. durum

Summary

TRITD2BV1G112850 (symbol TH7, also known as TtTH7) encodes a thioredoxin domain-containing protein with oxidoreductase activity acting on a sulfur group of donors, protein-disulfide reductase activity, and additional annotated functions including enzyme activator and inhibitor activities, salicylic acid and chitosan binding, and transcriptional co-regulator activity. In durum wheat, TH7 is associated with defense responses to bacteria, insects, and microbial phytotoxins, regulation of salicylic acid and jasmonic acid signaling pathways, systemic acquired resistance, and response to hypoxia. It localizes to multiple cellular compartments including the nucleus, chloroplast stroma, endoplasmic reticulum, and plasmodesmata. The gene is associated with responses to powdery mildew, stripe rust, common root rot, bacterial blight, and Cercospora leaf spot, as well as drought sensitivity, aluminum response, leaf senescence, and stomatal closure. Related genes in other species link the family to oxidative stress tolerance, pathogen resistance, and salt stress tolerance.