ICDH — Triticum turgidum subsp. durum

Summary

TRITD2BV1G181300 (symbol ICDH, also known as TtICDH or TtCICDH) on durum wheat chromosome 2B encodes an isocitrate dehydrogenase (NADP⁺), an enzyme of the isocitrate/isopropylmalate dehydrogenase family (EC 1.1.1.42). The gene is associated with NADPH regeneration, the TCA cycle, the glyoxylate cycle, and NAD(P) metabolism, and has been linked to brassinosteroid-mediated signalling and defence responses to bacteria. The encoded protein localises to plastids, mitochondria, chloroplast thylakoid and stroma, the cytosol, and the apoplast. Associations with proline content, salinity tolerance, photosynthetic rate, and root morphology traits have been recorded, as have connections to redox homeostasis, histone methylation, and leaf hydraulic conductivity. Studies of related genes in other species link the family to drought tolerance, oxidative stress response, chlorophyll content, and net photosynthetic rate.