GAD — Triticum turgidum subsp. durum

Summary

TRITD2BV1G158460, symbol GAD and preferred name TtGAD2, encodes a glutamate decarboxylase (EC 4.1.1.15) with pyridoxal phosphate-dependent decarboxylase and transferase domains, and also exhibits sphinganine-1-phosphate aldolase activity. The enzyme binds calmodulin and pyridoxal phosphate, and is associated with the GABA shunt, glutamate and sphingolipid breakdown, mRNA transcription, carboxylic acid metabolism, response to water, seed germination, and homeostasis. It localises to the ER membrane, ER, and cytosol. The gene is linked to growth stage and germination rate. Studies of related genes in other species connect the family to grain, seed, root, and shoot phenotypes, as well as dwarfism and sterility, while sequence similarity links the family to grain yield, sugar content, drought tolerance, and salt tolerance.