CYP51 — Sorghum bicolor

Summary

SORBI_3005G109800 (CYP51) on sorghum chromosome 5 encodes obtusifoliol 14-alpha demethylase, a cytochrome P450 family protein with sterol 14-demethylase, monooxygenase and oxidoreductase activities, and is annotated for brassinolide synthase and tabersonine 16-hydroxylase activities. The gene is associated with brassinosteroid biosynthesis and homeostasis, sterol metabolism and biosynthesis, indole alkaloid metabolism and biosynthesis, diterpenoid and saponin biosynthesis, demethylation, digestion, and response to light stimulus. Its product localises to the endoplasmic reticulum membrane and membrane, and is linked to sterol biosynthesis and secondary metabolism pathways. Studies of related genes in other species connect the family to growth stage traits.