CYP51 — Sorghum bicolor

Summary

SORBI_3005G109900, designated CYP51 on sorghum chromosome 5, encodes a cytochrome P450 protein belonging to the sterol 14α-demethylase family. The enzyme exhibits multiple annotated activities including brassinolide synthase, sterol 14-demethylase, piperitol synthase, and ent-kaurenoic acid monooxygenase activities, along with heme and iron binding. The gene is associated with brassinosteroid biosynthesis and homeostasis, sterol metabolism and biosynthesis, diterpenoid biosynthesis, demethylation, and paclitaxel anabolism. It has been linked to pollen tube development, digestion, and response to light stimulus. The product localizes to the endoplasmic reticulum membrane. Studies of related genes in other species connect the family to growth stage traits.