CYP79A1 — Sorghum bicolor

Summary

SORBI_3001G012300, symbol CYP79A1 on sorghum chromosome 1, encodes a cytochrome P450 enzyme with L-phenylalanine N-monooxygenase activity (EC 1.14.14.36) and related N-monooxygenase and hydroxylase activities. The gene is associated with cyanogenic glycoside and dhurrin biosynthesis, auxin (IAA) biosynthesis, tryptophan breakdown, camalexin biosynthesis, and secondary metabolite production. It has been linked to drought tolerance, leaf dry weight, and IAA content. Associations also include defense responses such as pathogen and insect resistance, callose deposition, systemic acquired resistance, and response to water. The encoded protein localises to the ER membrane and is connected to pollen exine formation, lipid hydroxylation, and electron transport. Studies of related genes in other species link these genes to glucosinolate and camalexin biosynthesis, auxin levels, and resistance to pests and diseases.

Annotations

Chromosome
1
Related genes
CYP79A1, CYP79A2, CYP79B2, CYP79C1, CYP79B3, F14A1.7, CYP79A3P
GO terms
GO:0005575, syngamy, NO storage, iron binding, Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Photosynthetic Electron Transport Chain, Monooxygenase Activity, Anther Development
Publications
23383346, 20032078, 15931500, 23209113, 20736450, 22870889, 22852809, 18414013
Traits
lateral root branching angle, indole glucosinolate biosynthesis, phenylacetic acid biosynthesis, Temperature-Dependent Reduction in Free IAA Levels, Early Senescence, Reduced Size, Early Flowering, Lower Auxin Levels, Subtle Growth Defects with Shorter Petioles and Smaller Leaves, IAN Treatment Restores Camalexin Synthesis, Hypersensitive to 5-methyltryptophan