CYP — Sorghum bicolor

Summary

SORBI_3001G041200, also known as SbSQN or CYP, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) on sorghum chromosome 1. The protein contains a cyclophilin-type PPIase domain and is annotated with diverse molecular functions including GTP:GDP antiporter activity, U5 and U2 snRNA binding, cyclosporin A binding, histone binding, chromatin binding, and structural constituent of ribosome. SbSQN is associated with numerous biological processes such as activation of secondary metabolite biosynthesis, regulation of ARF protein signal transduction, alternative mRNA splicing, basipetal auxin transport, and negative regulation of the hypersensitive response. It localizes to multiple cellular compartments including the mitochondrial ribosomal small subunit, Golgi stack, multivesicular body, stress granule, and trans-Golgi network. The gene is linked to agronomically relevant traits including variegated leaf, bacterial disease response, temperature stress response, starch grain synthesis, sucrose content, root hair length, chloroplast development, jasmonic acid content, arsenic concentration, stomatal opening, leaf senescence, flowering time, and seed development.