GST8 — Sorghum bicolor

Summary

SbGST8 (SORBI_3001G065800) on sorghum chromosome 1 encodes a glutathione S-transferase (GST) with glutathione transferase and ATP hydrolase activities, belonging to the Tau-like and thioredoxin-like superfamilies. The gene is associated with glutathione metabolism, detoxification, and responses to herbicides, drought, and red/far-red light. It is linked to toxin breakdown, including 2,4,6-trinitrotoluene, and to processes such as meristem growth, root and shoot development, inflorescence development, and gamete generation. Associations with agronomic traits include grain size, seed size, chlorophyll content, photosynthetic rate, herbicide sensitivity, disease tolerance, and zinc sensitivity. The encoded protein localizes to multiple cellular compartments, including the cytosol, chloroplast stroma, mitochondria, apoplast, and proteasome. Studies of related genes in other species link the GST family to drought tolerance, salt tolerance, herbicide detoxification, and oxidative stress responses.