GAD — Sorghum bicolor

Summary

SORBI_3001G111000 (SbGAD) encodes a pyridoxal phosphate-dependent decarboxylase with sphinganine-1-phosphate aldolase activity, calmodulin and calcium ion binding, and is classified as EC 4.1.1.15. This sorghum gene on chromosome 1 is associated with glutamate and sphingolipid breakdown, GABA formation, and responses to mechanical stimuli and calcium ion detection. It has been linked to grain yield, flowering time, seed development, leaf senescence, root development, shoot growth angle, stomatal closure, drought and heat stress tolerance, water-use efficiency, bacterial pathogen resistance, and abscisic acid sensitivity. The encoded protein localises to the ER membrane, plastid, mitochondria, cytosol, nucleus, and plasmodesmata. Studies of related genes in other species connect the family to submergence response, grain length, osmotic and temperature stress tolerance, and herbivory resistance.