CAM1 — Sorghum bicolor

Summary

SORBI_3001G237500 (SbCAM1) on sorghum chromosome 1 encodes a major facilitator superfamily (MFS) profile domain-containing protein with sugar transporter signatures. The gene product is associated with diverse molecular functions including carbohydrate transmembrane transporter activity, monosaccharide transmembrane transporter activity, symporter activity, S-nitrosoglutathione reductase activity, calcium ion binding, and chaperone protein binding. SbCAM1 has been linked to biological processes such as cellular responses to cold, drought, and salinity, leaf senescence, seed development, heat acclimation, programmed cell death, and the ERAD pathway. It localizes to the tonoplast, chloroplast envelope, plastid, mitochondria, and chromatin. Associations with agronomic traits include photosynthetic rate, flowering time, disease tolerance, root development, stem elongation, stomatal opening and closure, iron sensitivity and concentration, and abscisic acid sensitivity. Studies of related genes in other species connect the family to salt, drought, cold, and freezing tolerance, formaldehyde detoxification, and root development.