HSP70 — Sorghum bicolor

Summary

SORBI_3001G034400 (HSP70) on sorghum chromosome 1 encodes an uncharacterized protein with ATP-dependent protein folding chaperone, heat shock protein binding, ATP hydrolase, and ATP binding activities, belonging to the HSP70_C superfamily. This gene is associated with protein folding in the ER, protein refolding, the ERAD pathway, the ER unfolded protein response, response to virus, detoxification, protein breakdown, protein folding, programmed cell death, response to stress, response to heat, and cell death. Localization evidence links the product to the axonemal central pair projection, ER chaperone complex, ER lumen, chloroplast membrane, tonoplast, membrane, cytoplasm, and nucleus. The gene is also associated with heat tolerance. Related genes in other species are annotated as heat shock 70 kDa protein, but these are not established for sorghum.